YANG-MING INSTITUTE OF BIOMEDICAL INFORMATICS
首頁   陽明大學      ENGLISH VERSION

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  • 結構生物學 ( Structural Biology)
  • 超導核磁共振學 (NMR Spectroscopy)
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  • Y.R. Chen, H.B. Huang, C.L. Chyan, M.S. Shiao, T.H. Lin and Y.C. Chen. (2006) The Effect of Ab Conformation on the Metal Affinity and Aggregation Mechanism Studied by Circular Dichroism Spectroscopy. J. Biochem.139:733-740.
  • Chia-Lin Chyan, Po-Chung Huang, Tai-Hsien Lin, Jian-Wen Huang, S. S. Lin, Hsien-bin Huang and Yi-Chen Chen. (2005) Purification, crystallization and preliminary crystallographic studies of a Camodulin-OLFp molecule. Acta Cryst., F 61:785-787
  • Lou, B.-S., Lin, T.-H and Lo. C.-Z. (2005) The interactions of phenytoin and its binding site in DI-S6 segment of Na+ channel voltage-gated peptide by NMR spectroscopy and molecular modeling study. J. Peptide Res. 66:27-38.
  • Ta-Hsien Lin, Pai-Chi Tsai, Hsin-Tzu Liu, Yi-Chen Chen, Lan-Hsin Wang, Fu-Kai Hsieh and Hsien-Bin Huang. (2005) Characterization of the Protein Phosphatase 1–binding Motifs of Inhibitor-2 and DARPP-32 by Surface Plasmon Resonance. J. Biochem. 138:697-700.
  • Yu Ho, Jye-Chian Hsiao, Min-Hsiang Yang, Che-Sheng Chung, Yu-Chang Peng, Ta-Hsien Lin, Wen Chang and Der-Lii M. Tzou. (2005) The Oligomeric Structure of Vaccinia Viral Envelope Protein A27L is Essential for Binding to Heparin and Heparan Sulfates on Cell Surfaces: A Structural and Functional Approach Using Site-specific Mutagenesis. J. Mol. Biolo. 2005;349:1060-1071.
  • Lin, T.H., Huang, H.B., Wei, H.A., Shiao, S.H., Chen, Y.C. (2005), “The effect of temperature and lipid on the conformational transition of gramicidin A in lipid vesicles”, Biopolymers, Published Online: 11 Mar 2005; DOI: 10.1002/bip.20269.
  • Chou, C.Y., Lin, Y.L. Huang, Y.C., Sheu, S.Y., Lin, T.H., Tsay, H.J., Chang, G.G. and Shiao, M.S. (2005), “Structural Variation in Human Apolipoprotein E3 and E4: Secondary Structure, Tertiary Structure, and Size Distribution”, Biophys. J., 88, 455-466.
  • Lin, T.H, Huang, J.W., Huang, H.B., Chen, Y.C., Liu, C.Y., Lo, C.J., Tang, T.C. & Chyan, C.L. (2004), “Letter to the Editor: 1H, 15N, and 13C resonance assignments of calmodulin complexed with the calmodulin-binding domain of calcineurin”, J. Biomol. NMR, 29, 531-532.
  • Lou, B.-S., Lin, T.-H and Lo. C.-Z (2004), “The conformation and movement of Na+ channel inactivation gate peptide in linker between domain III and IV during inactivation by NMR spectroscopy and molecular modeling study”, J. Peptide Res., 63, 313-323.
  • Lin, T.H., Huang, Y.C., Chin, M.L., Chen, Y.C., Jeng, H.H., Lin, F.M., Shiao, M.S., Horiuchi, A., Greengard, P., Nairn, A.C. and Huang, H.B. (2004), “1H, 15N, and 13C resonance Assignments of DARPP-32 (dopamine and cAMP-regulated phosphoprotein, Mr. 32,000) – a Protein Inhibitor of Protein Phosphatase-1″, J. Biomol. NMR, 28, 413-414.
  • Lin, T.H., Chen, Y.C, Chyan, C.L., Tsay, L.H., Tang, T.C., Jeng, H.H., Lin, F.M. and Huang, H.B. (2003), “Phosphorylation by glycogen synthase kinase of inhibitor-2 does not change its structure in free state”, FEBS Lett., 554, 253-256.
  • Lin, T.H., Chia, C.M., Hsiao, J.C., Chang, W., Ku, C.C., Hung, S.C. and Tzou, D.L. M. (2002), “Structural Analysis of the Extracellular Domain of Vaccinia Virus Envelope Protein, A27L, by NMR and CD Spectroscopy”, J. Biol. Chem., 277, 20949-20959.
  • Liu, H.T., Lin, T.H., Kuo, H.C., Chen, Y.-C., Tsay, H.J., Jeng, H.H., Tsai, P.C., Shie, F.K., Chen, J.H. and Huang, H.B. (2002), “Identification of the Alternative Splice Products Encoded by the Human Protein Phosphatase Inhibitor -1 Gene”, Biochem. Biophy. Res. Commun., 291, 1293-1296.
  • Chyan, C.L., Tang, T.C., Chen, Y.C., Liu, H.T., Lin, F.M., Liu, C.K., Hsieh, M.J., Shiao, M. S., Huang, H.B. and Lin, T.H. (2001), “Backbone 1H, 15N, and 13C resonance assignments of inhibitor-1 – a Protein Inhibitor of Protein Phosphatase-1”, J. Biomol. NMR, 21, 287-288.
  • Huang, H.B., Chen, Y.C., Horiuchi, A., Tsai, L.H., Liu, H.T., Chyan, C.L., Hsieh, M.J., Liu, C.K., Lin, F.M., Greengard, P., Nairn, A. C., Shiao, M.-S. and Lin, T.H. (2001), “Letter to the Editor: Backbone 1H, 15N, and 13C resonance assignments of ARPP-19″, J. Biomol. NMR, 19, 383-384.
  • Huang, H.B., Chen, Y.C., Tsai, L.H., Wang, H.C., Lin, F.M., Horiuchi, A., Greengard, P., Nairn, A.C., Shiao, M.S. and Lin, T.H. (2000), “Letter to the Editor: Backbone 1H, 15N, and 13C resonance assignments of inhibitor-2 - a protein inhibitor of protein phosphatase-1″, J. Biomol. NMR, 17, 359-360.
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